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Polyglutamine diseases

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This has systemic effects throughout the body, potentially benefiting muscle tissue, bone density, fat metabolism, and overall cellular health

We first measured GNMT activity in these cells by quantifying secreted sarcosine in the cell culture media using the sarcosine oxidase assay ( Figure 5B )

To effectively target ferroptosis in OA, both the induction of ferroptosis by immune mediators and the adaptive changes of metabolic reprogramming must be considered