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Low glutathione levels have been linked to abnormalities in the lungs' lining, and having normal glutathione levels may protect from inflammation by protecting lung tissue from free radical damage.27 Additionally, animal studies found that intravenous glutathione supplementation helped maintain normal lung function and prevent damage such as decreased lung compliance, increased swelling, and reduced lung tissue

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To this end, a non-eosinophilic inflammation, dysregulated immune homeostasis, and mitochondria-mediated airway epithelial cell apoptosis were ameliorated via the ROS/ASK1 (apoptosis signal-regulating kinase 1)/MAPK pathway after apigenin treatment [186]