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Selection of the best combination of spectral filters for each biochemical parameter in an ensemble mode using ANN When the filter combination optimization for each parameter was performed, it was possible to define that the most frequent spectral filters for smoothing, baseline correction, normalization, and others were WDS, AsLS, SNV, and 1 st quadratic derivative, respectively (Table 3)

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When assessing insulin secretion by ex vivo GSIS, we found lower insulin output in response to glucose in Slc7a11 -KO mouse islets (45% in GSIS), corroborating our in vivo findings and supporting an islet intrinsic defect over a systemic adaptation

Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances