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Description

In IBD, the expression of phospholipase ATP8B1 is negatively correlated to the disease onset [171], whereas PS is positively correlated [172]

These stimuli first activate MEKK1-4, TAOs, transforming growth factor B activating kinase (TAK) and ASK, which mediate the p38 pathway and gradually activate MAPK kinases (MEK3/6) and p38 isoforms