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This is due to its ability to activate antioxidant, anti-apoptotic, and AMPK-linked pathways

Stable Systemic Markers: Circulating IGF-I levels and bone resorption markers show minimal fluctuation, supporting tissue-focused effects rather than generalized anabolic overstimulation

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After concentrating the culture medium using a 10 kDa filter, the secreted proteins were resuspended in RIPA buffer and subjected to a click reaction with azide-biotin, allowing biotinylation of the ITalk-labeled proteins