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Calles C, Schneider M, Macaluso F, Benesova T, Krutmann J, Schroeder P

Woreta, Johns Hopkins Medicine, Baltimore, MD and Saleh A Alqahtani, Johns Hopkins University School of Medicine

Their enhanced bioactivity relative to bulk copper is primarily attributed to the higher density of grain boundaries at the nanoscale, which facilitates accelerated copper ion release and promotes the generation of ROS (Sundberg et al., 2015)