Cargo selection in these pathways is often achieved via the binding of an autophagy receptor that harbors a consensus LC3-interacting region (LIR), a stretch of 4 amino acids to facilitate its direct binding to the LDS (LIR-docking site) of LC3 orthologs
ISBN 978-0-525-57451-4
IGF-1 is a highly anabolic peptide hormone responsible for: Muscle cell proliferation and repair Tendon and ligament regeneration Bone growth Glucose uptake in muscle cells Increased satellite cell activation Oral administration of MK-677 raised serum IGF-1 levels by over 60% in healthy adults without altering cortisol, insulin, or gonadotropin concentrations. Chapman et al., Clinical Pharmacology & Therapeutics This rise in IGF-1 is what leads to muscle growth, improved recovery, and increased physical resilience over time
Ingredients WATER, METHYLPROPANEDIOL, GLYCERIN, BETA-GLUCAN, DIMETHICONE, NIACINAMIDE, CYCLOPENTASILOXANE, BETAINE, POLYGLYCERIN-3, ALGAE EXTRACT, ECLIPTA LEAF EXTRACT, CENTELLA EXTRACT, FIG FRUIT EXTRACT, LICORICE EXTRACT, PANAX GINSENG EXTRACT, ULMUS DAVIDIANA EXTRACT, CAUDATUS SEED EXTRACT, LECITHIN, KERNEL OIL, SODIUM ACRYLATE/SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER, SODIUM POLYACRYLATE, ETHYLHEXYL STEARATE, ISOHEXADECANE, PANTHENOL, DIMETHICONOL, BUTYLENE GLYCOL, GLUTATHIONE (1000PPM), RICE FERMENT, SORBITAN OLEATE, TRIETHOXYCAPRYLYLSILANE, TRIDECETH-6, SQUALANE, FRUCTOOLIGOSACCHARIDES, HYDROGENATED POLYSOBUTENE, DISODIUM EDTA, ISONONYL ISONONANOATE, POLYGLYCERYL-10 STEARATE, CETEARYL ALCOHOL, STEARIC ACID, SHEA BUTTER, POLYGLYCERYL-2 DIPOLYHYDROXYSTEARATE, HYALURONIC ACID, INULIN LAURYL CARBAMATE, PEARL POWDER, CARBOMER, CERAMIDE NP, DISODIUM STEAROYL GLUTAMATE, PALMITOYL PENTAPEPTIDE-4, POLYSORBATE 80, POLYSORBATE 20, FRANGRANCE, 1,2-HEXANEDIOL, HYDROXYACETOPHENONE, TITANIUM DIOXIDE (CI 77891) *** Ingredients are subject to change at the manufacturer's discretion
