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doi:10.3389/fphar.2022.1026182

Benefit 04 Systemic Anti-Inflammatory Effects BPC-157 modulates the COX-2 inflammatory pathway and reduces pro-inflammatory cytokine production

A aggregation and tau hyperphosphorylation can disrupt the calcium balance in neurons, leading to mitochondrial calcium overload, increased reactive oxygen species production, reduced ATP generation, and ultimately, neuronal apoptosis or necrosis [76, 77]