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To explore the role of p38 MAPK in ferroptosis-induced VEGFA and IL8 induction, ESCs were treated with erastin in the absence or presence of the p38 inhibitor, SB203580 (10 M) for 12 h

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In fact, the RVI event was shown to be inhibited during apoptotic processes (Maeno et al., 2006b), through the Akt1 inhibition caused by ROS-induced ASK1 phosphorylation (Subramanyam et al., 2010)