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Through the continuous integration of multimodal technologiesincluding microfluidic chips, high-content imaging, AI, and genome editingthe zebrafish model not only supports an end-to-end pipeline from compound screening to toxicological evaluation but also demonstrates strong potential for translational applications encompassing target discovery, mechanism elucidation, and clinical correlation

Parkin-mediated protection of dopaminergic neurons in a chronic MPTP-minipump mouse model of Parkinson's disease

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CRC Press, Boca Raton, pp 7583 Tsai C-H et al (2018) Ocular drug delivery: role of degradable polymeric nanocarriers for ophthalmic application