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219 B Vitamins A number of studies have found that people with obstructive sleep apnea, particularly those with severe disease, have higher levels of homocysteine, an amino acid linked to increased risk of cardiovascular and neurodegenerative diseases

10.1186/s13287-022-03056-y 285 RashidiM.BijariS.KhazaeiA

Taken together, these data validate the structural model of the two binding sites, and show that the long helix provides the most binding affinity, while binding to the F-pocket provides a substantial enhancement of binding