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The reference nutrient intake (RNI) for adults in the UK is 1.5 micrograms daily, though therapeutic doses for treating deficiency are substantially higher

Low Birth Weight & Preterm Labor Low B12 levels are associated with increased risks of intrauterine growth restriction (IUGR) and preterm delivery [*]

However, individual response varies significantly depending on baseline nutrient status, genetic factors affecting nutrient metabolism, and overall metabolic health rather than the injection alone

Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy