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With intramuscular (IM) injections the standard treatment for severe deficiency or malabsorption conditions like pernicious anaemiaserum B12 levels rise rapidly, typically reaching therapeutic ranges within 2448 hours after the first injection

The cause is multifactorial: reduced caloric intake, slower gastric emptying, mild dehydration if water intake drops with appetite, and elevated B12 demand during a rapid metabolic shift

Researchers have thought there could be a connection between vitamin B 12 deficiency and MS for a long time

Anti-Inflammatory Activity Several experimental studies have observed reduced inflammatory signaling in gut tissue following administration of BPC-157