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Significant and independent prognostic factors at PD associated with favorable PFS were ECOG PS score 0 and Child-Pugh A

J Biol Chem 278(4):22942303

In contrast to the reversibly hyperoxidized cysteine sulfenylated proteins, irreversibly hyperoxidized sulfonylated cysteine is generally thought to be an impaired dead end product (e.g., inactivated protein) formed through protein aggregation 25