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doi: 10.1016/j.cell.2017.09.021 81 LimJKMDelaidelliAMinakerSWZhangHFColovicMYangHet al

The why and how of amino acid analytics in cancer diagnostics and therapy

Loss of LKB1, occurring in 1530% of NSCLC cases, leads to profound metabolic reprogramming characterized by increased glycolysis, impaired OXPHOS, altered mitochondrial dynamics, and dysregulated nutrient sensing

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