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Nat Rev Mol Cell Biol 10 , 843853 (2009)

Among these agents, sotorasib (AMG 510) and adagrasib (MRTX849) have emerged as promising therapeutic options, demonstrating notable clinical efficacy in patients with KRAS G12C-mutant NSCLC (85,94)

Research found that Tunicamycin administration increased the Prevotellaceae to Erysipelotrichaceae ratio in the GM of liver-injured mice, a trend reversed by Berberine treatment