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Gastroenterology 164 , 619629 (2023)

"The FDA continues to use its regulatory and enforcement authorities to address the illegal marketing and distribution of unapproved drugs, including products marketed as peptides for human use

The Bottom Line: Compelling Mechanisms Demand Rigorous Human Investigation BPC-157 presents a fascinating scientific paradox: extensive preclinical evidence spanning three decades demonstrates pleiotropic effects across multiple neurotransmitter systems, with antidepressant efficacy exceeding standard drugs in animal models, anxiolytic effects without dependence liability, neuroprotection in stroke and neurodegeneration models, and reversal of schizophrenia-like cognitive deficits

This is why continuous dosing is the standard in every major clinical trial