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10.1016/j.ejphar.2007.11.071 114 McEwenB

We dissect each clathrin box by mutagenesis to track their occupancy by the Ent1 and Ent2 adaptors and show that both Ent1 and Ent2 exhibit different Chc binding patterns, as revealed by native MS and photobleaching FRET assays

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Because physical exercise increases demand on a weakened heart, measures of exercise tolerance are frequently used to monitor the severity of heart failure