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They work on a cellular level, and that takes time

Murawski, M

Additionally, Syn constructs containing a C-terminal cysteineSyn 1103 -104C and Syn S129E -141Cwere generated by site-directed mutagenesis for MST-based binding studies, as previously described 35

Using this property, glutathione can be cross linked to an agarose bed, which then captures GST or GST tagged protien via their substrate binding interaction