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Nanocarriers of antigen proteins for vaccine delivery

The therapeutic effect of KDS12025 in neurodegenerative mouse models, including AD, PD, and ALS Reactive astrocytes play a pivotal role in neurodegeneration by promoting oxidative stress and neuronal damage, which are hallmarks of AD, PD, and ALS pathology

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In keeping with the reduced capacity of homocysteine-exposed endothelial cells to inhibit platelet aggregation, Lentz and collaborators demonstrated, using experimental hyperhomocysteinemia (induced by a diet depleted of folate, high in methionine, and choline-free) that the endothelial-dependent vasodilation is impaired in hyperhomocysteinemic primates