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Crossref Selim MSM, Abdelhamid SA, Mohamed SS

DOI: 10.1016/j.archoralbio.2017.04.017 20

Overall, experience from the oncology field suggests that amino acid metabolism intervention is more likely to be implemented through well-defined clinical development strategies, including monotherapy or combination therapy, dose escalation, safety monitoring, and immune pharmacodynamic endpoints, and may provide a useful framework for trial design and stratification in immune-mediated diseases