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Description

Cancers 14 , 5110 (2022)

Given that both MitoQ and DPI target mitochondrial function, we used the Loewe synergy model, which is particularly suited for evaluating the combined effects of drugs with similar mechanisms of action (36)

A.EbadiZVan HerckMet al

Unlike patient-specific neoantigens, which require individualized immunotherapeutic development 1,2,3 , commonly mutated oncoprotein-derived epitopes presented on class I major histocompatibility complex (MHC) molecules provide an opportunity to target cancer-specific antigens shared across patient populations 4,5