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2) BDNF exerts bidirectional regulation of GABAergic transmission by inhibiting GABA signaling in mature GABAergic neurons while enhancing GABA transmission and facilitating LTD in immature GABAergic neurons via the pro-BDNF/p75 neurotrophin receptor (p75(NTR)) pathway (166, 167)

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What the Research Gap Means in Practice Honesty demands acknowledging the obvious: the human clinical data on stacking BPC-157 with GLP-1 agonists is essentially nonexistent