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In the rapidly progressive A pathology model 5xFAD, male and female mice often exhibit non-overlapping phenotypes across ages and brain regions, with particularly prominent differences in amyloid plaque burden and the associated glial responses [70, 71], consistent with our findings

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Arg II results in reduced NO synthesis by competing with eNOS for the same substrate, l-arginine (115117)

In this method, a special double-stranded DNA sequence containing the NF-B response element was immobilized onto the bottom of the wells of a 96-well plate