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Zinc and copper are known cofactors for thyroid hormone metabolism and antioxidant defense systems, which may explain the pronounced response in the ZnO-NPs and Cu-NPs groups 83

This finding warrants further investigation to determine whether peripheral expression of this transporter could serve as a useful biomarker for neurodegenerative diseases

Total Flavones from Semen Cuscutae, the main component of Cuscuta seeds from the plant Cuscuta chinensis Lam ., is known for improving endocrine function, enhancing sexual function, and exhibiting antioxidant and immunomodulatory effects [111]

While erastin is primarily known as a ferroptosis inducer through its inhibition of SLC7A11-mediated cystine uptake [31], its potential therapeutic application in periodontitis requires careful consideration