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Description

This manuscript looks at the use of ancillary testing in the diagnosis of cystic fibrosis

40 ChiveroE

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The mutant huntingtin protein does not affect the PINK1/Parkin pathway but disrupts the interaction of mitophagy adaptors OPTN, CALCOCO2, SQSTM1/P62, and NBR1 with LC3, leading to impaired fusion of mitochondria and autophagosomes and a compromised mitophagy mechanism (144)