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It works by activating GLP-1 receptors in your brain to promote satiety and reduce hunger and food cravings

This is the primary reason the American Academy of Pediatrics recommends supplementing breastfed infants with 400 IU per day (formula is fortified with vitamin D, so the levels are consistent, which is why this recommendation is solely for breastfed infants)

Kosiborod MN, Deanfield J, Pratley R, Borlaug BA, Butler J, Davies MJ, et al

Muscle Contraction Frequency Research In vitro cellular studies using cultured muscle cells examined Syn-AKEs direct effects on contractile activity[2]: 71% reduction in muscle contractions within 1 minute of 0.025% peptide application 58% reduction maintained after 2 hours of exposure Dose-dependent response with optimal activity at 0.5-4% concentrations Reversible effects upon peptide removal without permanent muscle changes These findings established the rapid-onset, sustained-duration profile that characterizes Syn-AKEs neuromuscular effects