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AIMS: To evaluate the prevalence and risk factors for hepatocellular carcinoma development in previously treated chronic HCV patients in an outpatient hepatology clinic at "Hospital das Clinicas" of University of So Paulo School of Medicine, So Paulo, Brazil

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Shown are in vitro ubiquitylation assays like that in Fig

Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism