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doi: 10.1055/s-2001-18358

Loci from a genome-wide analysis of bilirubin levels are associated with gallstone risk and composition

Circulation 135, 10081010

95,96,97 NAD + and aging An imbalance in the NAD + /NADH or NADP + /NADPH ratio can destabilize cellular homeostasis, causing not only pellagra but also aging, neurodegenerative diseases, inflammatory alterations, infections, cardiovascular diseases, and cancer