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GPX4 plays a pivotal role in regulating lipid peroxides within cells and the reduction in GSH and GPX4 that we demonstrate in the IB3-1 AECs following FAC and erastin treatment is likely responsible for the increased lipid peroxidation that we found, as evidenced by the increase in MDA and C11-BODIPY

Antifungal Activity Several investigations have reported the antifungal activity of biogenic SeNPs

CONCLUSIONS Together, this evidence suggests that oxidative stress and in particular disturbed glutathione metabolism are related to the pathogenesis of hypertension