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5 However, N-Acetylcysteine (NAC) may cause increased histamine release from mast cells resulting in side effects in sensitive people and contradicting the beneficial effects from anti-inflammatory actions

The potential benefits and risks should be carefully assessed

However, how changes in the redox status itself could impact the intracellular Ca 2+ homeostasis in astrocytes is not known, although this could be of great help to understand the neuronal damage caused by oxidative stress

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