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Eccentric exercise is acknowledged for the generation of a local inflammatory response in the skeletal muscle with the timing and peak of neutrophil infiltration linked to the magnitude of muscle function decrements [66, 67]

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The GSH moiety of the drug has to be processed by GT before further processing by dipeptidases to generate dimethylarsino-cysteine (DMAC), a cysteine S -conjugate which is imported via cystine transporters ( Figure 4 )

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