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Intraventricular injection of CNTF in EAE mice reduced expression of inflammatory cytokines TNF- and interferon- and decreased demyelination and neurodegeneration (117)

tricornutum is crucial for basic research and practical applications

In MS, clinical therapies aimed to block TNF--mediated pro-inflammatory effects (Van Oosten et al., 1996

Dysfunction of vmPFC activity may be common to mood disorders and independent of mood state because it has been described in both unipolar (97, 98) and bipolar depression as well as in the context of elevated mood (95, 99)