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10.1093/jme/tjab035

Nonclinical, in vitro proof of concept has been achieved for NPI-001 in HCCAA, with the demonstration that NPI-001 catabolizes L68Q-hCC-induced high molecular weight complexes that cause HCCA

Furthermore, BCG recognizes different Mycobacterium tuberculosis molecular patterns through primed intracellular Toll-like receptors (TLRs) 7 and 9 in M, activating intrinsic immune transcription and gene expression profiles through the NFB pathway to TLR signaling (200)