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Congruently, expression of glutamine synthase (GS), an effector molecule of the -catenin pathway which is expressed by peri-central hepatocytes, increased significantly by IF in pIVCL mice livers compared to sham (fold change 1.85, p value 30%, and veterans for whom LSM was obtained after HCC diagnosis were excluded

In another study, luteolin (1 mg/kg) was assessed in vivo in OVA-sensitized BALB/c mice [158]

In line with this, suppressed fructose uptake has been found to reduce leukemogenesis and intensify the cytotoxicity of Ara-C in fast-proliferative cells in the BMME