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Most hypotheses assume that BTX-A inhibits the release of Ach as well as other neurotransmitters, including inhibition of the release of substance P or the blocking of autonomic pathway

42 Another RCT studied cyano-B12, 1500 g three times per day for 2 weeks (route not reported), in patients with seasonal affective disorder and found no improvements in either the B12 or the placebo group

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