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Administration results in competitive antagonism at the motor end-plate, which decreases both the miniature end-plate potential (MEPP) and the muscle's response to exogenously applied acetylcholine

Dong H, Wang Y, Zhang X, et al

But the COAs often tell consumers nothing about whether the manufacturer has put the right amount of a substance in a vial

TB-500 at loading dose of approximately 2 to 2.5 milligrams twice weekly for the first two weeks, then maintenance at 2 milligrams once weekly for four to six additional weeks