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Description

NAD+-metabolizing ectoenzymes in remodeling tumorhost interactions: the human myeloma model

Regular retesting intervals allow for treatment optimization and ensure that therapeutic blood levels are maintained over time

Reactions were performed with 5 M histone H3 (histone L-arginine) substrate, 1 M radiolabeled S-adenosyl-L-[methyl-3H]methionine (SAM) co-substrate, and recombinant human PRMT3 enzyme