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KimDHLeeYKLeeSDKimSHLeeSRLeeHGet al

(45) described a subset of children with CVS with prolonged and severe emetic phase associated with profound lethargy, hypertension and laboratory evidence of HPA axis hyper-responsiveness and increased secretion of antidiuretic hormone (ADH)

Our studies identify a histone acetylation pathway promoted by KG production that is indispensable for HR proficiency and corresponding resistance to DNA-damaging agents