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Additionally, the ME of PPs biosynthetic pathways might increase the long-term resistance of recombinant plants to invasive fungal pathogens and decrease the application of chemical fungicides, though this benefit will require further large-scale investigations to confirm its efficacy against crop fungal pathogen damages

A critical gap is that aspartate does not appear to have been tested directly at metabotropic G protein-coupled glutamate receptors (mGluRs) [100]

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These observations are consistent with the relative affinities of the sensor variants determined in vitro (Fig