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Another analog of 5-HI, N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]-2-oxopiperidine-3-carboxamide (HIOC), also a derivative of N-acetylserotonin, has been found to activate tyrosinase kinase B (TrkB) receptor signaling [10], protecting the retina from light-induced degeneration [10]

Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents

Thus, in vertebrates, Grx3 may be important for iron delivery to mitochondria primarily in erythropoietic tissues, which have very high requirements for iron