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doi: 10.1016/j.addr.2010.09.001 110 HatakeyamaH.AkitaH.ItoE.HayashiY.OishiM.NagasakiY.et al

NAD + also plays a critical role in other aspects of mitochondrial function, which must be maintained to ensure cellular health through several dynamic and coordinated homeostatic pathways

hence, it is more preferable than cyanocobalamin for the treatment of vitamin B12 deficiency (1,2,3,4)

Whilst vitamin B12 side effects stomach-related are uncommon, some individuals experience mild gastrointestinal symptoms when taking supplements, particularly oral formulations