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Some progress has been made in many aspects, from the cellular level to the molecular biological level, from experiment to clinic, catalpol shows considerable therapeutic promise, but its clinical application is limited by the intricate biochemical pathways it affects

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Antivir Ther 19:773782 Barillari G, Iovane A, Bacigalupo I, Labbaye C, Chiozzini C, Sernicola L, Quaranta MT, Falchi M, Sgadari C, Ensoli B (2014) The HIV protease inhibitor indinavir down-regulates the expression of the pro-angiogenic MT1-MMP by human endothelial cells