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TE is often triggered by physiological stressors, hormonal fluctuations, nutritional deficiencies, or certain medications, leading to a temporary but significant increase in hair shedding

Under normal physiological conditions, they are largely self-sustaining, maintaining their population through local proliferation within the CNS, minimizing reliance on circulating monocytes [19, 20]

Phase 2 trial data published in the New England Journal of Medicine (2023) demonstrated average reductions in body weight exceeding 20% over 48 weeks in some participants