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One potential way to counteract this process is to increase your collagen intake from foods like bone broth, or use a collagen supplement

Glia 69(6):14131428 Li Y, Xia Y, Yin S, Wan F, Hu J, Kou L et al (2021) Targeting microglial -synuclein/TLRs/NF-kappaB/NLRP3 inflammasome axis in Parkinsons disease