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DSIP also influences the release of met-enkephalin and beta-endorphin in the hypothalamus

M.BronzeriF.de Cassia RochaA.et al (2022)

At the center of this network was HSPA8, a regulator chaperonin-mediated autophagy inhibitor of syn aggregation, which has been implicated in PD, DLB, MSA, and other neurodegenerative diseases [35, 50]