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Li et al , 2019

J Ethnopharmacol 114:412416 Ning H, Xin ZC, Lin G, Banie L, Lue TF, Lin CS (2006) Effects of icariin on phosphodiesterase-5 activity in vitro and cyclic guanosine monophosphate level in cavernous smooth muscle cells

Moreover, during oxidative stress GSSG can also be exported from the cytosol either to the exterior or, in yeast, to the vacuole to maintain a reducing cytosolic environment (Ballatori et al , 2009