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These results highlight the potential of PDA@Pt as an effective and safe alternative for treating gout, providing a promising strategy for the development of novel therapeutic agents against this disease

At high concentrations, NO can react with superoxide to form peroxynitrite (ONOO ), a potent oxidant that depletes GSH and initiates lipid peroxidation, thereby driving ferroptosis

15 Quercetin has been demonstrated to prevent neuronal injury via inhibition of oxidative stress mediated inflammation (via NLRP3 inflammasome activation) in microglia through promoting mitophagy (breakdown of mitochondria, particularly those which are dysfunctional), which provides a potential novel therapeutic strategy for neuroinflammation-related diseases

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