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Description

Despite a comprehensive understanding of two main mitochondrial pathways, intrinsic apoptosis and mitochondrial permeability transition (mPT)-driven necrosis, in acute and chronic degenerative diseases, the development of an effective therapeutic strategy remains a major challenge 2,3

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A threshold BA-LRA score of 0.22 was set to predict clinical DILI

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The 13 C-labelled metabolite ratio analysis and human 13 C-labelling dynamics were done using MATLAB (R2020a)

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