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FIGURE 2 This figure depicts the dysregulation of the HPA axis in PTSD, highlighting the altered cortisol secretion patterns due to impaired negative feedback

Disulfide linkers exploit the high level of intracellular reduced glutathione to release free drug inside the cell

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endothelial NOS, neural NOS, and iNOS) exerts different effects on -cell function [48], and in most cases, the eNOS/nNOS-derived NO has physiological relevance, whereas iNOS-derived NO in general has pathological effects